Associate Director, International Tax

Overview 

We are seeking a strategic and experienced Associate Director of International Tax to be a key partner in global tax planning, compliance, and reporting across our multinational operations. This role will serve as a key advisor to senior leadership, ensuring alignment of tax strategies with business objectives while maintaining compliance with evolving international tax regulations.

The ideal candidate will bring deep expertise in cross-border taxation and global tax structuring, along with strong leadership and partnership skills.

This is a hybrid position and will be primarily located in Cambridge, MA.

Responsibilities

• Lead global tax strategy and planning to optimize effective tax rate and cash tax position
• Provide technical expertise on U.S. international tax matters (GILTI, FDII, Subpart F, BEAT, OECD Pillar Two)
• Support M&A, restructurings, and global expansion through tax planning and modeling
• Ensure accurate reporting, including CFC filings, Forms 5471/8858, and country-by-country reporting
• Develop and maintain tax models to forecast effective tax rates, cash taxes, and impacts of structural or legislative changes
• Deliver data-driven insights to support strategic decision-making
• Identify and manage global tax risks, maintain internal controls, and support audits and tax authority inquiries
• Partner cross-functionally with Finance, Treasury, Legal, and executive leadership to support business initiatives and market expansion
• Support global transfer pricing strategy, including policies, intercompany agreements, and audit defense
• Lead external advisor relationships, drive process improvements, and leverage technology to scale tax operations
• Support international tax compliance and global tax provision (ASC 740 / IFRS), partnering with internal teams and external advisors, as needed

Qualifications

• Bachelor’s degree in accounting, finance, or related field (Master’s in Tax preferred)
• 8-10+ years of international tax experience in public accounting and/or a multinational organization
• Deep expertise in U.S. international tax (GILTI, FDII, Subpart F, BEAT) and familiarity with OECD Pillar Two
• Experience with tax provision (ASC 740), global compliance, and reporting processes, preferred
• Proven ability to build and leverage tax models for forecasting and scenario analysis
• Experience with OECD Pillar Two implementation preferred
• Experience operating in a publicly traded or high-growth environment preferred
• Familiarity with ERP and tax technology tools (e.g., SAP, Oracle, OneSource) preferred
• CPA, JD, MST, or equivalent certification preferred

U.S. Pay Range

$170,000.00 - $230,000.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.