Associate Director, Research (Targeted Delivery)

Overview

The Research Department at Alnylam is seeking an Associate Director to lead a team responsible for advancing RNAi therapeutics into the future, by opening up targeted delivery to all tissues. The individual will need excellent collaboration and communication skills, connecting team members from multiple areas. The successful candidate will have excellent knowledge of biochemistry/biological sciences with experience in receptor identification/characterization (unbiased screens) and affinity ligand discovery (antibody, peptide, etc.), This role requires in-depth expertise in tools and techniques to identify receptors and characterize ligand-receptor interactions. Expertise in ligand selection approaches (e.g. phage display, yeast display) is essential. Experience in the field of antibody drug conjugates is a plus.

This position is onsite and will be primarily located in Cambridge, MA.  

Key Responsibilities

• Lead an interdisciplinary team to execute goals of targeted delivery into new cell types and tissues.
• Manage external collaborations relating to receptor identification and ligand development for targeted delivery.
• Establish tools, techniques and assays to identify new receptors, develop new binding ligands, and characterize ligand-receptor interactions, which may include recombinant protein production, binding assays, and cell-based assays to assess receptor engagement and functional siRNA delivery. 
• Transparently communicate results with key stakeholders throughout the organization.

Qualifications

• PhD in Biochemistry, Molecular Biology, Cell Biology, or related field.
• 8+ years of experience in biopharma setting.
• Expertise in ligand selection approaches and receptor biology.
• Strong background and in-depth understanding of protein chemistry, receptor identification, biochemical characterization of ligand-receptor interactions including binding and uptake.
• Experience in the field of antibody drug conjugates and nucleic acid conjugates will be a plus
• Strong track record of working in interdisciplinary, collaborative team-based research environment and leadership of research projects.
• Excellent communication skills (both written and oral) are essential.
  
  

U.S. Pay Range

$169,000.00 - $238,200.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.