Director, People Operations

Overview 

The Director, Regional People Operations will manage the People Operations function, systems and services across the region. This role is accountable for building a high‑performing team, continuously improving processes, and partnering across HR Centers of Excellence to ensure organizational alignment. Reporting to the VP, People Experience, this position plays a critical role in advancing how HR delivers an Efficient, Effective, and Exceptional Experience across the organization!

This is a hybrid position and will primarily be based in Cambridge, MA.

Responsibilities

• Lead People Operations transformation initiatives, partnering across HR to evolve systems, processes, and ways of working that collectively enable an Efficient, Effective, and Exceptional Experience.
• Build, develop, and lead a high‑performing People Operations team, establishing clear operating standards, accountabilities, and a culture of continuous improvement.
• Design and continuously enhance employee experiences across the end‑to‑end people lifecycle using a process‑driven, customer‑focused approach.
• Partner closely with HR Business Partners and Centers of Excellence to deliver integrated, enterprise‑aligned solutions.
• Leverage data, analytics, and systems insights to identify gaps, address limitations, and drive measurable operational improvements.
• Drive a strategic approach to the development of People Operations, continuously seeking out best practices and evaluating opportunities for automation where appropriate.
• Act as a trusted advisor across HR functions, ensuring People Operations capabilities enable enterprise priorities and employee experience outcomes.

Qualifications

• 10+ years of related experience required, with a strong background in human resources, consulting, and/or a comparable field.
• Bachelor’s degree or equivalent required.
• Proven experience building and leading high‑performing teams within complex, matrixed, or global organizations, including leading teams through change.
• Strong systems and process orientation, with demonstrated success driving continuous improvement initiatives.
• Ability to balance standardization with flexibility to meet diverse customer and business needs.
• Demonstrated ability to manage a team is a must.
• Demonstrated change in management skills and drive & influencing skills needed.

#LI-MH1 #LI-Hybrid

U.S. Pay Range

$191,300.00 - $258,700.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.