Director, U.S. Commercial Technology

Overview

Alnylam is the world’s leading RNA interference (RNAi) company, dedicated to transforming the lives of patients through innovative medicines. As we expand our commercial presence in the U.S., we are evolving our technology operating model to deliver greater efficiency, scale, and business alignment. The Director, U.S. Commercial Technology will play a pivotal role in shaping and executing the technology strategy for our U.S. Commercial organization, ensuring that our systems, data, and digital capabilities enable commercial excellence and support our mission.

Responsibilities

• Serve as the primary technology leader and business partner for the U.S. Commercial organization, building strong relationships with commercial leadership and stakeholders to understand business objectives, priorities, and technology needs.
• Develop deep expertise in U.S. Commercial business objectives and processes, proactively identifying opportunities where technology can support and enhance key business goals.
• Lead the delivery, support, and continuous improvement of commercial technology platforms (e.g., CRM, data management, omnichannel engagement, analytics), ensuring they are robust, scalable, and aligned with enterprise standards.
• Drive the adoption of the IT operating model within the U.S. Commercial team, emphasizing centralized governance, in-house leadership, and seamless integration with enterprise IT and business partners.
• Oversee the lifecycle of commercial technology solutions, including requirements gathering, vendor management, implementation, and ongoing support, with a focus on optimizing processes, data quality, and user experience.
• Establish and enforce technology governance, standards, and best practices for the U.S. Commercial organization, including data privacy, security, and compliance.
• Collaborate with U.S. Commercial teams (Sales, Market Access, Operations, Marketing and Patient Services) and cross-functional teams (Regulatory, Data & AI, IT Strategy and Operations, Security & Compliance) to ensure technology solutions support end-to-end commercial processes and enterprise-wide integration.
• Provide system training to business and technical colleagues; collaborate with the Training & Learning Development team to develop training materials and programs.
• Support and guide the Application Support teams (e.g., Veeva CRM support), and optimize the allocation of responsibilities across internal and external teams.
• Proactively identify areas for improvement and address functional gaps in system setups.
• Research and evaluate new technologies and third-party applications to enhance system functionality and business value.
• Use root cause analysis and troubleshooting skills to resolve functional and technical issues.
• Act as an escalation point for complex technology issues impacting the U.S. Commercial organization.

Qualifications

• Degree in Information Technology, Data Science, Computer Science, or related field, with specialized knowledge in clinical development and analytics.
• Proven business analysis skills with excellent analytical and problem-solving abilities.
• Effective prioritization and project management skills.
• Significant experience in CRM, sales intelligence, sales force effectiveness, business analysis, or business analytics in regulated industries, such as healthcare or biopharma.
• Experience supporting commercial functions in the U.S. market; knowledge of U.S. healthcare and commercial landscape preferred.
• Knowledge of a range of commercial business systems and tools.
• Strong team player with the ability to maintain effective relationships at all levels.
• Ability to anticipate, understand, and address changing business and departmental needs.
• Excellent communication skills, both oral and written.
• Leadership and/or supervisory experience.

U.S. Pay Range

$187,400.00 - $253,600.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.