Sr. Manager, Invoice to Pay

Custom Field 1:  2580
Date:  Oct 30, 2025
Location: 

Cambridge, MA, US, 02142

Sr Manager, Invoice to Pay

 

Position Summary:

The Senior Manager, Accounts Payable will be responsible for managing the operational functions and activities of a fast-paced, Accounts Payable Department ensuring work requirements are performed in a timely and accurate manner, using data analytics and automation to drive the daily processes; establishing and maintaining efficient and effective processes; and providing exemplary internal and external customer service as a representative of the company. The Senior Manager Accounts Payable will be expected to become a valuable mentor and leader to our Global Accounts Payable Team by providing clear communication and instruction or training when needed and should possess leadership skills that empower and engage the team. This position reports to the Global Process Owner P2P

 

Key Responsibilities:

  • Lead and manage the Global Accounts Payable team, fostering a culture of excellence, collaboration, and continuous improvement.
  • Build effective relationships and provide excellent stakeholder service across the company with various departments (Accounting, Operations, Commercial, Treasury, IT, HR, Audit, Marketing, Legal) and act as a business partner on Accounts Payable matters and inquiries.
  • Develop and implement strategies to enhance the efficiency and scalability of payments function.
  • Set direction for the Accounts Payable function to align with Finance team goals and support continuous improvement, analytics and automation across processes, systems, and team performance.
  • Drive strategic initiatives within AP, including enhancing use of systems (SAP VIM, Ariba), and reducing manual or inefficient tasks.
  • Identify and implement technology solutions and automation to streamline workflows and increase transparency in the AP process.
  • Oversee the accuracy and timeliness of monthly close activities related to AP, including accruals, reconciliations, and vendor aging reviews.
  • Oversee the day-to-day operations of processes, ensuring accuracy and timeliness in payment processing, financial reporting, transaction processing, and data reconciliation.
  • Serve as the escalation point for complex vendor issues, payment discrepancies, or policy exceptions, working cross-functionally to resolve root causes.
  • Maintain and enforce internal controls within AP, ensuring proper segregation of duties, approval workflows, and compliance with company policies.
  • Support audit and compliance efforts (e.g. 1099's) by ensuring the AP function is well-organized, documented, and responsive to inquiries.
  • Ensure compliance with all relevant accounting standards, regulations, and internal policies, mitigating risks and safeguarding the company’s financial integrity.

 

Minimum Requirements/Qualifications:

  • 7+ years of work experience with 5+ years in leading a Global Accounts Payable team
  • Prior operational experience using data analytics and automation within the Procure to Pay cycle is a must
  • Experience of SAP Ariba, VIM would be a plus
  • Proven ability to interact with multiple levels of stakeholders both internally and externally
  • Self-directed, dynamic, and customer-centric change-agent who thrives in a challenging and changing environment
  • Highly collaborative; aligns effectively with colleagues and business partners to deliver results while maximizing the success of all contributors
  • Skilled communicator and proven relationship builder, able to operate within a multitude of formal and informal networks while managing the competing interests of varied stakeholders
  • Champions productivity improvements through Process Improvement and has a commitment to continuous learning
  • Bachelor’s Degree Required
  • Excellent attention to detail required
  • Business acumen to develop effective partnerships with key stakeholders and provide a strategic perspective in discussions and communications

U.S. Pay Range

$131,800.00 - $178,300.00

The pay range reflects the full-time base salary range we expect to pay for this role at the time of posting. Base pay will be determined based on a number of factors including, but not limited to, relevant experience, skills, and education. This role is eligible for an annual short-term incentive award (e.g., bonus or sales incentive) and an annual long-term incentive award (e.g., equity).

Alnylam’s robust Total Rewards package is designed to support your overall health and well-being. We offer comprehensive benefits including medical, dental, and vision coverage, life and disability insurance, a lifestyle reimbursement program, flexible spending and health savings accounts and a 401(k)with a generous company match. Eligible employees enjoy paid time off, wellness days, holidays, and two company-wide recharge breaks. We also offer generous family resources and leave. Our commitment to your well-being reflects our belief that caring for our people fuels the impact we create together.

Learn more about these and additional benefits offered by Alnylam by visiting the Benefits section of the Careers website: https://www.alnylam.com/careers

About Alnylam

We are the leader in RNAi therapeutics – a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.

At Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.


Nearest Major Market: Cambridge
Nearest Secondary Market: Boston